You are unique. And so is RYTARY.*

Every RYTARY capsule contains a unique combination of time-released carbidopa/levodopa (CD/LD) beads.

pills
*Compared to IR CD/LD.

This is what makes RYTARY different.

Together, these beads allow RYTARY to work (absorb) quickly—and keep working for up to 4 to 5 hours—to treat the symptoms of Parkinson’s disease.

In comparison, IR CD/LD medications only provide an immediate dose of medication. Levodopa levels look like a series of peaks and valleys over the course of a day.

The chart below is based on a single-dose study of RYTARY in healthy volunteers; pharmacokinetic level was projected over 12 hours.

comparison-graph

RYTARY works to smooth out those peaks and valleys created by IR CD/LD by quickly delivering levodopa and then extending levodopa levels over a longer period of time. This may reduce the amount of “off” time you experience each day.

When I told my doctor about how often I was experiencing ‘off’ time, we talked about switching to extended release RYTARY. Our hope was that it would keep me on a more even keel, and it does do that for me.
Individual results may vary.
Phil
ON RYTARY
SINCE 2015

Let RYTARY help the real you
shine through.

Taking RYTARY may result in:
2X
reduction in “off” time compared with Immediate-Release (IR) CD/LD

In a clinical study, people with advanced Parkinson’s disease taking RYTARY experienced a 13.1% reduction in “off” time during waking hours (compared with only 6.2% for people taking IR CD/LD).

  • RYTARY at study start and study end§: 36.9% to 23.8%
  • IR CD/LD at study start and study end§: 36.0% to 29.8%
Better movement control

RYTARY also improved motor symptoms compared with IR CD/LD, which may help you perform daily activities.||

“Waking hours” is a term used to describe the hours during a day in which you are awake. The primary measurement in this study was the percentage of “off” time during waking hours.
§Study end = Week 22 or early termination.
||This was a secondary measure of the study.
I have more ‘on’ time with RYTARY. Parkinson’s doesn’t stop me from stretching and staying physically active as my doctor recommended.
Individual results may vary.
Debbie
ON RYTARY
SINCE 2015

RYTARY was shown to have
a similar safety profile as IR CD/LD.

In a clinical study, the most common side effects occurring in at least 5% of people treated with RYTARY and at a higher rate than IR CD/LD were nausea and headache.
I wasn’t surprised when I had a little trouble with nausea at first, and a slight dose adjustment was needed. RYTARY definitely gives me more ‘on’ time, so it’s been a great choice for me.
David, on RYTARY since 2016
Ask your healthcare provider if RYTARY could be right for you.
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